he Canadian dairy industry adds $16.2 billion to Canadian GDP each year (2011 figures). That figure is forecast to increase as international demand for dairy products grows in the coming years, due to growing middle classes in emerging economies, demand for high-quality milk proteins in developing countries and world population expansion more generally. That figure can also grow (by an estimated $100 million annually) by improving two key traits in dairy cattle: their ability to convert feed into increased milk production and a reduction in their methane emissions (methane being a powerful greenhouse gas). Dr. Filippo Miglior of the University of Guelph and Dr. Paul Stothard of the University of Alberta are leading a team that will use genomics-based approaches to select for cattle with the genetic traits needed for more efficient feed conversion and lower methane emissions. To date, it has been both difficult and expensive to collect the data required for such selection. The latest genomic approaches and the award-winning phenotyping platform developed by Growsafe in Alberta offer an opportunity to address these problems and collect and assess the required data to carry out the selection. The results of this project will assist dairy farmers and the industry more broadly to develop cattle that will carry these two important traits. Farmers will save money (as feed is the single largest expense in milk production), while the international competitiveness of Canada’s dairy industry will increase. The environmental footprint of the dairy industry will also be reduced, in part due to lower methane emissions, but also because more feed efficient animals produce less manure waste. Broad application of the project’s findings will be enhanced by the involvement of several industry organizations and international research partners in the project, not only benefiting Canada’s dairy industry, but also contributing to global food security and sustainability.
Towards a sustainable fishery for Nunavummiut (2014)
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Affordable access to safe, nutritious and culturally relevant food is one of the biggest challenges facing the Nunavummiut, the people of Nunavut. Food costs are 140 per cent higher in Nunavut than in the rest of Canada with eight times more Inuit households facing moderate to severe food insecurity. This lack of affordable, nutritious foods is linked to growing health problems, including diabetes and childhood rickets. Accelerated melting of Arctic sea ice due to climate change is increasing access to arguably the last remaining under-exploited fishery in the Northern Hemisphere. This increased accessibility, primarily to Arctic char, but also to Arctic cod and Northern shrimp, coupled with a developed, sustainable, science-based fishing plan will offer opportunities for employment and economic benefits for Nunavut communities as well as greater food security. It is the Nunavummiut that should be the beneficiaries of these resources, rather than foreign fishing fleets. Understanding the genetic differences among these fish populations is key to developing that plan. Dr. Virginia K. Walker of Queen’s University and colleagues together with the Nunavut communities will integrate traditional and local knowledge with leading-edge genomic science and bioinformatics to gain an understanding of the genomes of these fish populations. This will allow monitoring of their migration, characteristics and adaptation and inform strategies to maintain genetically diverse and healthy stocks. The project will work toward strengthening Nunavut fisheries, augment sovereignty claims in the Canadian Arctic, increase employment and economic development opportunities, ensure access to a healthy food source, and improve food security for the people of Nunavut. The Walker Project website is www.arcticfishery.ca
The University of Toronto, Dr. Michael Garton in collaboration with MyoPalate: Establishing the foundational tools for cultivated pork production
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Overview
Growing pork meat in bioreactors using pig stem cells has the potential to positively impact environmental and animal rights issues. However, while the technology to do this is established, it is currently prohibitively expensive. A high proportion of this cost is due to the costly external biological and chemical agents required for pig muscle development and maturation. The Garton team, in partnership with Myo Palate, proposes to design synthetic gene circuits that can be integrated with the initial stem cells and direct muscle transformation and maturation processes, obviating the need for external agents. Establishing this proof-of-concept will lay the groundwork for developing a comprehensive genetic circuit for directing pig muscle development in bioreactors.
The proposed project will lay the groundwork for improving the efficiency of cultured meat production. By introducing genetic circuits, the cells will be better able to carry out their differentiation program without the requirement for adding additional soluble factors like recombinant proteins or additives. In addition, the project will improve the safety and lower the cost of cellular agriculture by minimizing the number of components needed to culture meat. Successful completion of this project will establish an engineering biology tool kit for the production of lab-grown pork, which will benefit Ontario’s cellular agriculture food business ecosystem by enhancing cell behaviour at a sustainable cost.
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