Enhanced human hematopoietic stem cell engraftment by modulation of SIRPa-CD47 interactions between donor and recipient (2009)


Human Health


A joint effort by researchers at The Hospital for Sick Children and the University Health Network is developing a test to help predict the outcomes of hematopoietic stem cell transplants – commonly referred to as bone marrow transplants – based on the genetic make-up of the potential donor and recipient. This prognostic test would aim to predict (and therefore decrease) complications that can occur in transplant patients such as transplant failure and graft versus host disease.