The Canadian Precision Health Initiative (CPHI) is a $200M investment from the Government of Canada, through Genome Canada, to help transform Canada’s healthcare approach into a modern, precision health system.
Supported by the regional Genome Centres, including Ontario Genomics, this initiative will build Canada’s largest-ever collection of human genomic data —more than 100,000 genomes. This database will represent Canada’s diverse population to ensure precision health innovations benefit all.
CPHI partners will work together to build a coordinated precision health community that will:
- Build a Canadian alliance for genomics in health to align efforts across Canada’s complex, federated health and research ecosystems.
- Mobilize and advance the utility of genomic health data, working with academia and industry to ensure they have the right data assets and AI-powered tools to deliver life-saving solutions.
- Implement data governance and policies ensuring the ethical and responsible use of genomic data.
Ontario Genomics is the lead for 4 awarded projects and the co-lead for 2 awarded projects. These projects will help generate high-quality genomic data that can be shared and securely used by researchers and clinicians across Canada. Learn more about these projects below:
Expanding the Use of Genomics to Unravel Rare Diseases: Care4Rare EXPAND
Project Leaders: Kym Boycott (University of Ottawa/Children’s Hospital of Eastern Ontario Research Institute), Christian Marshall (University of Toronto/Hospital for Sick Children), Francois Bernier (University of Calgary), Jacques Michaud (Université de Montréal/CHU Ste Justine)
Genome Centres: Ontario Genomics, Genome Alberta, Génome Québec
INFANT: Identifying At-risk Newborns from the Analysis of NGS Testing
Project Leaders: Kristin Kernohan, Neal Sondheimer, Melanie Lacaria, Erika Bariciak, Pranesh Chakraborty, Matthew Henderson (Children’s Hospital of Eastern Ontario Research Institute)
Genome Centre: Ontario Genomics
Precision Child Health – Comprehensive Sequencing for Childhood Life-long Disorders
Project Leaders: Stephen Scherer, Seema Mital, David Malkin, Linda Hiraki, Amanda Ricciuto, Gregory Costain, Yiming Wang, Ronald Cohn (Hospital for Sick Children)
Genome Centre: Ontario Genomics
Precision Health Network for Neurodevelopment, Mental Health and Brain Injury
Project Leaders: Evdokia Anagnostou (Holland Bloorview Research Institute), Jennifer Crosbie, Stephen Scherer, Louise Gallagher (The Hospital for Sick Children), Jacob Vorstman (Hospital for Sick Children), Darcy Fehlings (University of Toronto/Holland Bloorview Research Institute), Roger Zemek (Children’s Hospital of Eastern Ontario Research Institute), Danielle Andrade (University Health Network)
Genome Centre: Ontario Genomics
Genomic Evidence for Precision Medicine for Selected Chronic Diseases among Black Peoples in Canada
Project Leaders: Upton Allen (Hospital for Sick Children), Loydie Jerome-Majewska (McGill University), OmiSoore Dryden (Dalhousie University), Juliet Daniel (McMaster University)
Genome Centres: Genome Atlantic, Génome Québec, Ontario Genomics
Longitudinal, Deep-Phenotyped Pediatric Databank of Medical and Drug Therapy Outcomes
Project Leaders: Bruce Carleton (University of British Columbia), Michael Rieder (University of Western Ontario), Maja Krajinovic (Université de Montréal)
Genome Centres: Genome British Columbia, Genome Alberta, Génome Québec, Ontario Genomics