Rapid, accessible genome assembly using long read sequencing


Human Health


DNA sequencing technology has progressed from sequencing single reference genomes at great cost and time, to the current era of inexpensive, high-throughput short read sequencing. The emerging “third generation” of DNA sequencing technology offers the prospect of putting long read genome sequencing in the hands of more researchers and enabling new applications, through portable instruments that will decentralize sequencing technology.

Dr. Jared Simpson of the University of Toronto is developing robust and efficient genome assembly software that is easy to use, to match the capabilities of these emerging sequencing instruments. The software will target biologists and other end users of sequencing who don’t have substantial bioinformatics expertise.