Ontario Genomics Institute /
2012 Annual Report

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Genomics has increased our understanding of the human body and disease, leading to improved diagnoses, treatments and longer, healthier lives.

Projects actively funded in 2011–2012

Biomonitoring 2.0: A high-throughput genomics approach to comprehensive biological assessment of environmental change

→ Mehrdad Hajibabaei

University of Guelph
July 2011 – June 2014
$3.1 Million

NorCOMM2 – In vivo models for human disease & drug discovery

→ Colin McKerlie

Mount Sinai Hospital, Toronto

→ Steve Brown

Medical Research Council Harwell (UK)
July 2011 – June 2014
$10.9 Million

Synthetic antibody program: commercial reagents and novel therapeutics

→ Sachdev Sidhu, Charles Boone

University of Toronto
July 2011 – June 2014
$9.9 Million

Therapeutic Opportunities to Target Tumor Initiating Cells in Solid Tumors

→ Tak Mak

University Health Network, Toronto
June 2010 – May 2014
$40.0 million

Development of Highly Active Anti-Leukemia Stem Cell Therapy (HALT)

→ John Dick, Jean Wang

University Health Network, Toronto
April 2010 – March 2014
$31.8 million

Genomics for Crop Improvement: Agricultural Pest Management

→ Miodrag Grbic

University of Western Ontario, London
October 2009 – September 2013
$6.3 million

Bioproducts and Enzymes from Environmental Metagenomes (BEEM)

→ Elizabeth Edwards

University of Toronto

→ David Major

Geosyntec Consultants, Guelph
October 2009 – September 2013
$11.0 million

Finding of Rare Disease Genes in Canada (FORGE Canada)

→ Kym Boycott

Children’s Hospital of Eastern Ontario Research Institute, Ottawa
April 2011 – March 2013
$4.1 Million

The Centre for Applied Genomics (TCAG)

Science & Technology Innovation Centre

→ Stephen Scherer

Hospital for Sick Children, Toronto
January 2006 – March 2013
$14.4 million

International Barcode of Life (iBOL)

→ Paul Hebert

University of Guelph
July 2008 – December 2012
$19.8 million

Structural Genomics Consortium (SGC) – Phase III

→ Aled Edwards

University of Toronto
University of Oxford (UK)
July 2011 – June 2012
$16.2 million

Structural Genomics Consortium (SGC) – Phase II

→ Aled Edwards

University of Toronto
University of Oxford (UK)
Karolinska Institute, Stockholm (Sweden)
July 2007 – June 2011
$118.5 million

Structural and Functional Annotation of the Human Genome for Disease Study

→ Robert Hegele

Robarts Research Institute, London
October 2006 – June 2011
$21.6 million

Dollar amounts are total approved project costs as of March 31, 2012