Genetic Determinants of Human Health and Disease: Annotation of Chromosome 7
Website: www.chr7.org
Summary
The Stem Cell Genomics Project
Summary
Stem cells have extraordinary potential to help in the treatment of some of the most intractable diseases - for example, arthritis, diabetes, neurological conditions such as Parkinson's and Alzheimer’s, and stroke. They are not yet available for this purpose because of lack of basic knowledge about stem cells. Full exploitation of their potential requires understanding of the genetic factors that make them what they are and of how they specify different kinds of cells and tissues in the body.
Genetic Determinants of Human Health and Disease
Summary
This research program explored gene variants causing and/or modulating a number of common multigenic disorders, including Alzheimer’s, cancer (breast, endometrial, melanoma, ovarian, and prostate), inflammatory bowel disease, and osteoporosis. The research team also developed biometric and computational tools for expediting discovery of disease genes.
