Technologies for Methylome Studies
Summary
Over the last decade a series of new methods have been developed to investigate DNA methylation profiles across large DNA regions - chromosomes and even entire genomes. Unfortunately, all these methods exhibit significant limitations as they require large amounts of DNA, interrogate only a small fraction of methylatable nucleotides or are able to scan only short DNA fragments. This Genome Canada project was dedicated to development of a new technology for genome- wide DNA methylation, or methylome, analysis.
Software Tools to Simplify Gene Function Prediction
Summary
In the late 1990s, Google brought the power of the web search to the average internet user by introducing a simple, intuitive interface backed by powerful analysis software and a massive data warehouse. By extending existing software prototypes to build the ‘Google of Biology’ - a software system that lets people use all existing genomics and proteomics data to answer specific biological questions about gene function - this current research project will bring the genomics revolution to the average biologist.
Proteomic Technologies for the Study of Rare Cells
Website: http://www.oisb.ca/technology/technology_development.htm
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