Pionyr Immunotherapeutics, a biotech startup, raises $62 million in series B investment round and is now planning to take its anti-cancer therapy to clinical trials.
It has been 15 years since the publication of the complete human genome. During that time, many organisms have been sequenced from crops and animals to simple organisms like bacteria. The Earth BioGenome Project (EBP) has proposed an audacious goal: to sequence, within a decade, the genomes of all 1.5m known species of plants, animals and fungi. The $500M project could create an enormous data resource that could help answer fundamental question, discover new drugs and materials, and more.
A new nanopore technology for direct sequencing of long strands of DNA has resulted in the most complete human genome ever assembled with a single technology, scientists have revealed. The research, published today in Nature Biotechnology, included scientists from the University of British Columbia and the Ontario Institute for Cancer Research (Jared Simpson, pictured above). Using an emerging technology – a pocket sized, portable DNA sequencer – the scientists sequenced a complete human genome, in fragments hundreds of times larger than usual, enabling new biological insights.
A proud day for all Canadians with the announcement of $255 million to support genomic innovations and advance precision health. Congratulations to all of the award-winning teams across Ontario and Canada.
With a $100,000 investment, Ontario Genomics is helping Toronto-based start-up company Bright Angel Therapeutics develop novel anti-fungal treatments. Fungal diseases are a global public health problem. Data compiled by the Global Action Fund for Fungal Infections (GAFFI) show that “over 300 million people are afflicted with a serious fungal infection and 25 million are at…
It’s not just diet and physical activity; your genes also determine how easily you lose or gain weight. Researchers at the Icahn School of Medicine at Mount Sinai and other institutions of the Genetic Investigation of Anthropometric Traits (GIANT) consortium found 13 genes that carry variations associated with body mass index (BMI). Some genes were linked to people who weighed above the average, and some below, and 8 of the 13 were newly implicated in obesity.
The use and recommendation of chemotherapy for women with both node-negative and node-positive early-stage breast cancer has declined in recent years, according to a recent survey. One of the survey authors, Dr. Allison Kurian, said in a press release “This likely reflects a change in the culture of how physicians are practicing, and a move toward using tumor biology to guide treatment choices rather than solely relying on clinical measures.” Lead author Dr. Steven Katz adds “Our study shows how breast cancer is a model for how doctors have driven advances in personalized medicine into the exam room to reduce overtreatment.”
Ontario Genomics is pleased to announce that two new rounds of Genome Canada’s Genomic Applications Partnership Program (GAPP) are now open.
The GAPP funds public-private research collaborations focused on developing genomics-derived technologies that address opportunities and challenges identified by industry, government, not-for-profits or other “Receptors” of genomics innovation. The program provides a unique opportunity for Receptor organizations to collaborate with an ’omics researcher, and to leverage their R&D investments with public funding.
Food Evolution, a new documentary by Academy Award™-nominated director Scott Hamilton Kennedy, was screened in Toronto and Waterloo this week. The film explores the polarized debate on genetically-modified organisms (GMOs) and food, and how both pro- and anti-GMO camps claim science is on their side. The documentary, narrated by the accomplished astrophysicist Neil deGrasse Tyson,…
Ranomics is a Toronto-based genomics company specializing in high-throughput mutagenesis and functional genomics screens, for the purpose of understanding genetic variations in human health. Leo Wan and Cathy Tie, who were both researchers at Mount Sinai Hospital at the time, founded the company in 2015. Both founders were distinguished scholars. Leo received his Ph.D. from…