Doctors in Europe used gene therapy to grow sheets of health skin that saved the life of a boy with a rare genetic disease that had destroyed most of his skin.
New research from Australia has shown that the combined affected pregnancy rate of cystic fibrosis, fragile X syndrome and spinal muscular atrophy is comparable to the population risk for Down syndrome. This highlights the need to offer carrier screening routinely, not just to those individuals with a family history.
Ontario Genomics has closed an investment in Rapid Novor, a Kitchener-Waterloo based biotech company that provides rapid, accurate, de novo protein sequencing services across Canada and internationally. This was another investment from the 2017 round of the Pre-commercial Business Development Fund (PBDF), which supports commercially promising ‘omics technologies. To date, Rapid Novor has offered monoclonal…
The appeal of precision medicine is the promise that we can understand disease with greater specificity and fashion treatments that are more individualized and more effective. A core tenet is that diseases such as type 2 diabetes may be a compilation of many subgroups, and that we can develop distinct treatments for each. But, at least outside of oncology, could there be an alternate tenet?
MIT scientists have engineered a new molecular system for efficiently editing RNA in human cells. Unlike the permanent changes to the genome required for DNA editing with CRISPR/Cas9, RNA editing is a potentially reversible way to make corrections in the cell, for instance as a treatment for rare diseases.
The Autism Speaks MSSNG team announced the upload of an additional 2,030 fully sequenced genomes to the project’s cloud-based databank – making it the world’s largest whole genome resource for autism research. The MSSNG team includes Dr. Stephen Scherer and the Hospital for Sick Children (SickKids) in Toronto, Autism Speaks and Verily (formerly Google Life Sciences).
Ontario Genomics is pleased to announce its investment in Ardra Inc. via its Pre-Commercial Business Development Fund. Ardra is a specialty chemicals company focused on the production of natural ingredients for the cosmetics and flavour and fragrance industries. Their synthetic biology platform uses designer biochemical pathways to produce a large portfolio of high-value products. Ardra’s development pipeline…
A genetic test that more accurately predicts the risk of developing breast cancer could soon be used on high-risk groups. Researchers behind the test, available in England only at this time, say it could reduce the number of women choosing pre-emptive mastectomy surgery. The blood test looks at 18 genetic variations, or single-nucleotide polymorphisms (SNPs), known to affect the chances of getting breast cancer.
Advances in precision medicine depend on the ability to share genomic information voluntarily, securely and responsibly. To achieve this, The Global Alliance for Genomics and Health (GA4GH) has struck formal collaborations with 15 international genomic data initiatives. Ontario and Canada lead or help drive at least three of these, CanDIG, ICGC-ARGO and Matchmaker Exchange. Genome Canada has also announced new operational funding for the GA4GH.
The Liberal government has whittled down the list of contenders eligible for a piece of its $950-million “supercluster” program, an initiative to foster innovation and create jobs in five specialized hubs across the country. The nine finalists on the government’s short list include partnerships in ocean and digital technologies, artificial intelligence, transportation, manufacturing, mining, agri-food and infrastructure. Ontario Genomics is pleased to see genomics as a key enabling technology in several of the supercluster initiatives.