Annotation of chromosome 7

April 4, 2001

Chromosome 7 contains many genes crucial to development, the cystic fibrosis gene, and is often damaged in some types of leukemia and other cancers. This project, led by Steve Scherer of the Hospital for Sick Children completed a gene map and applied it to disease study, and annotated all pertinent biological features contained in the DNA sequence of human chromosome 7. The project published a seminal manuscript in Science in 2003, describing an accurate DNA sequence and annotation of the entire human chromosome 7 – the first such paper of its kind. Products of this project have been distributed to over 350 investigators worldwide, many of which were probes sent for patient studies or diagnosis.

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