Three Ontario projects awarded a total of $12.6M in funding

December 12, 2017

In a recent announcement from Genome Canada, three Ontario projects were awarded funding from Round 8 of the Genome Canada Genomics and Applied Partnership Program (GAPP). Ontario Genomics was pleased to work with the teams in putting together the proposals. GAPP funds translational research and development projects that address real-world challenges and opportunities as identified…

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Canada and China partnering to develop diagnostics tests for preterm birth

November 30, 2017

BGI and Lunenfeld-Tanenbaum Research Institute, part of Sinai Health System, awarded investment from Genome Canada and Ontario Genomics PRESS RELEASE – Shenzhen, China and Toronto, Canada, November 30, 2017 ‒ BGI and the Lunenfeld-Tanenbaum Research Institute, part of Sinai Health System, today announced the signing of a Memorandum of Understanding (MOU) outlining their intention to…

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Applying genomic selection to improve health, welfare, efficiency and production traits in turkeys

May 31, 2017

Dr. Christine Baes of UofG and Ben Wood of Hybrid Turkeys will be collaborating to adapt and apply genomic tools to improve the health, welfare and productivity of Canadian turkeys. Hybrid Turkeys’ parent company, Hendrix Genetics, has already implemented genomic selection in chickens and pigs, and will now adapt and apply the technology to achieve improvements in feed efficiency, bodyweight, yield, egg production and livability in commercial turkeys. This will lead to estimated economic gains of $39 million over the next five years for the Canadian turkey industry, and will result in environmental benefits due to improved feed efficiency as well as reduced manure and greenhouse gas production.

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Increasing yield in canola using genomic solutions

May 31, 2017

Dr. Peter Pauls, Michael Emes, and Ian Tetlow of the UofG are working with Benson Hill Biosystems and its Canadian subsidiary, CanolaCo to produce more efficient varieties of canola for Canadian producers. Using a portfolio of trait candidates to improve photosynthesis-one of the most complex systems in plants-and developing these in canola, the project will enhance crop productivity by increasing photosynthetic capacity without negatively impacting seed quality. This will enable commercialization of the improved plants, with the enhanced yields of the canola crop enabling the industry to meet its goal of increasing yield by 53 percent in the next 10 years, growing industry revenues by an estimated $3-$4 billion per year.

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Translating ’OMICS for competitive dairy products

May 31, 2017

Dr. Gisele LaPointe of UofG is working with Maria Pepe of Parmalat Canada, the number one producer of premium aged cheddar in Canada, to increase Parmalat’s manufacturing capacity, and thereby gain efficiency and protect market share. To achieve this, the team will validate and implement metagenomic, metaproteomic and metabolomics tools modified to meet the technical requirements of cheese production. By improving manufacturing processes and controls, the project will overcome current bottlenecks and significantly increase the production capacity of high-quality, competitive, aged cheddar cheese –ultimately increasing the demand for and utilization of Canadian milk.

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Development of LSPR Sensor Technology for Next Generation Biosensors

May 16, 2017

Nicoya Lifesciences, a nanotechnology sensor company that builds novel products for the life sciences industry, is developing a new LSPR sensor chip technology that enables the accurate measurements of samples from crude or complex media such as water, food matrices, human saliva and more. With a granted patent on this technology, and demonstrated experimental proof of concept, Nicoya will utilise Ontario Genomics’ PBDF investment to begin to commercialize this novel sensor technology for the proteomics and genomics industry.

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Genome-based microbial community modeling

March 9, 2017

Elizabeth Edwards and Radhakrishnan Mahadevan of the University of Toronto are developing computational models using microbial genomes and metagenomes to uncover metabolic interactions in complex anaerobic microbial communities. They will identify and validate metabolic gaps pointing to metabolites exchanged among an anaerobic subsurface mixed microbial community that contains microbes used for bioremediation of toxic chlorinated solvents. This project aims to boost the efficiency of dechlorination in groundwater remediation, and resolve metabolic gaps in genome-scale models at the microbial community level.

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CRISPR/Cas9 conjugative plasmids for microbiome control

March 9, 2017

Drs. David Edgell and Gregory Gloor of the University of Western Ontario are working to develop and test a CRISPR/Cas9 conjugative plasmid system to enable precise user-defined manipulation of the composition of microbial communities. This novel microbial control system aims to enable the selective elimination of individual bacteria from a mixed population. If successful, the microbial control system has broad-ranging applications in basic biomedical research, industrial food-related process, and human health, bringing the scientific community one step further in the quest to harness the power of microorganisms to overcome humanity’s challenges.

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